This is a peer-reviewed paper in Nature providing an overview of opioid use disorder (OUD) and is written by a group comprised of many leading experts in the field. The paper discusses the epidemiology of OUD, especially as it relates to risk factors and burden. Next, the neuroscience and pathophysiology of OUD are discussed. The last half of the paper provides the evidence on strategies for prevention, early intervention, and treatment for OUD.
Strang, J., Volkow, N.D., Degenhardt, L., Hickman, M., Johnson, K., Koob, G.F., Marshall, B.D.L., Tyndall, M., Walsh, S.L. (2020). Opioid use disorder. Nature, 6(3), 1-28.