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Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement

This is an academic paper that provides an overview of the neurobiology and neuroscience of opioid use disorder (OUD), with diagrams showing the parts of the brain affected and the science underlying the high risk of recurrence of OUD symptoms. 

Resource Type
Peer-reviewed Articles and Reports
Continuum of Care
Prevention
Treatment
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Educational
Peer-reviewed Article
Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement
Citation

Koob, G.F. (2020). Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement. Biological Psychiatry, 87(1), 44-53.