This peer-reviewed article evaluates the PROSPER trial. PROSPER implemented school-based evidence-based prevention interventions for sixth graders in rural public school districts in Iowa and Pennsylvania. The findings showed that these strategies are effective in decreasing nonmedical prescription opioid use.
Crowley, D. M., Jones, D. E., Coffman, D. L., & Greenberg, M. T. (2014). Can We Build an Efficient Response to the Prescription Drug Abuse Epidemic? Assessing the Cost Effectiveness of Universal Prevention in the PROSPER Trial. Preventive Medicine, 62, 71–77. doi:10.1016/j.ypmed.2014.01.029