This is a report from the National Academy for State Health Policy (NASHP) that discusses the role that integrating substance use disorder treatment into primary care can play in mitigating the addiction crisis. Some of the topics discussed include Screening, Brief Intervention, and Referral to Treatment (SBIRT) and integrating medications for opioid use disorder (MOUD) into primary care. Considerations for state policies as well as payment and deliver reform are provided.