This issue brief from Trust for America's Health and Well-Being Trust provides national and state data from 1999-2017 on deaths of despair, which are defined as deaths attributed to drug overdoses, suicides, and alcohol poisoning/alcohol-related liver disease. 

This is an issue brief that provides an update on the first two "Pain in the Nation" reports. Opioid overdose deaths have declined but deaths involving alcohol, suicide, synethetic opioids, and psychostimulants continue to rise. Prior responses to the opioid crisis are highlighted, experts are interviewed, and recommendations are made. 

This is a report from the Institute for Patient- and Family-Centered Care that summarizes the Patient and Family Advisor (PFA) Summit on the opioid crisis, held in 2018. Characteristics of meaningful partnerships with patients and families are discussed and several promising partnerships are highlighted. Recommendations are made to strengthen these partnerships. 

This toolkit from the Harm Reduction Coalition provides examples of policies and practices from current peer-delivered syringe exchange (PDSE) programs. It gives an overview of points to consider in starting a PDSE program and is intended to generate new ideas for revising and improving existing PDSE programs.

This is a report from the Center for Public Safety Initiatives that provides a catalog and summaries of programs, approaches, and interventions to respond to the opioid crisis. These entries include responses that are local, national, and international. 

This paper describes Interact for Health, a foundation working to address the opioid crisis in Cincinatti, OH, with particular focus on funding strategy, outcomes, and lessons learned from 2008 to 2018. As an organization that awarded grants and helped build a community response to address the opioid crisis in an area that was hit hard and early, this paper offers lessons learned for communities and foundations currently implementing action plans. 

This is a report from the Open Society Foundation for law enforcement personnel on how to incorporate, support, and create space for approaches that aim to increase public safety and health, reduce harm to people who use drugs, and provide law enforcement alternatives to common punitive models.

This study sought to understand important changes in co-occurring opioid and nonopioid drug use (i.e., polysubstance use) within the opioid crisis in the United States. Past-month use of at least 1 nonopioid drug occurred in nearly all participants (> 90%) in this study.

This paper emphasizes that viewing opioid trends in a “silo” ignores the fact that polysubstance use is ubiquitous among those with opioid use disorder and that significant changes in polysubstance use should be monitored alongside opioid trends.

This is a toolkit developed by the North Carolina Department of Health and Human Services which gives communities strategies on how to establish a post overdose response team. This includes providing harm reduction strategies, naloxone, overdose prevention training, and overall ways to reduce overdose mortality. The toolkit provides four specific phases which explain how to design and implement the program and also make improvements. 

This is an academic paper which compares the impact of different overdose prevention site locations in Philadelphia, Pennsylvania. The authors did this comparison through the use of a mathematical model that predicts the behavior and demographic information of users. This paper also highlights which racial groups are more likely to benefit from the overdose prevention sites based on where in the city they are located. 

This is a toolkit from the Harm Reduction Coalition that is tailored to pregnant and parenting individuals, their families, and their service providers and has been written by people with lived experience. The overall goal is to improve the health and well-being of pregnant people who use substances and their families by providing information and resources with a harm reduction frame. 

Prescribe to Prevent was compiled by several naloxone access and overdose prevention advocates. The website provides information and resources on prescribing and dispensing naloxone.