Safe injection sites (SISs) are a harm reduction strategy that is being explored and have been implemented in some jurisdictions in Canada. 

This report summarizes the literature assessing the impact and effectiveness of SISs as a harm reduction strategy. SISs are successful in engaging high-risk and marginalized individuals who use substances, including regular and long-time users, individuals experiencing homelessness and those who were previously incarcerated.

SISs facilitate access to health and social services, reduce syringe sharing and public syringe disposal, as well as prevent on-site fatal overdoses. Establishing a SIS requires consultation of a wide range of stakeholders (e.g. the public, police, health and social services, and people who use substances) throughout the process.