This paper describes the Post Overdose Support Team (POST), a person-centered initiative led by Massachusetts harm reductionists in health and human services agencies in collaboration with municipal first responders. POST teams conduct home-based outreach with individuals who experienced an opioid-related overdose, providing a menu of services including naloxone rescue kits, overdose response and risk reduction planning, referral to treatment for substance use disorders including medication for opioid use disorder, and referral to recovery and family supports.