This report from the CDC shows overdose deaths by age, gender, race/ethnicity, urban/rural community, and selected states over the time period 1999 to 2018.
Hedegaard, H., Miniño, A.M., Warner, M. (2020). Drug overdose deaths in the United States, 1999–2018. NCHS Data Brief, no 356. Hyattsville, MD: National Center for Health Statistics.